What are keratinocytes?

Keratinocytes are the most common type of cell found in the epidermis, the outermost layer of the skin as well as the hair follicle niche we cryopreserve at Acorn. They are responsible for producing the protein keratin, which gives the skin its strength and elasticity. Keratinocytes are also involved in the process of wound healing, by migrating to the site of an injury and forming new skin.

In regenerative medicine, keratinocytes can be used to treat a variety of skin conditions, including burns, wounds, and certain types of skin cancer. One way this is done is by culturing keratinocytes in a laboratory, and then transplanting them onto the affected area. The keratinocytes can then differentiate into the different cell types found in the epidermis, and begin the process of forming new, healthy skin.

Keratinocytes have also been used as a model system to study the underlying mechanisms of skin diseases, and to develop new treatments for these conditions.

In addition, keratinocytes can be reprogrammed into other cells, such as induced pluripotent stem cells (iPSCs) and then differentiate into any kind of cells in the body. This can be a powerful technique for regenerative medicine as it allows researchers to create replacement cells and tissue to treat various diseases and injuries.